Hair Loss In Men

Hair loss is more common in men than in women and can affect males as early as their late teens and early 20s. Male pattern hair loss follows the Rule of Decades: 20% of males in their 20s suffer from pattern baldness; in men in their 30s, 30% experience hair loss, and so on.

Men usually experience hair loss at the crown (bald spot at the back of the head), front (receding hairline) and top of the scalp. 95% of all male hair loss cases is due to male pattern hair loss, which is genetically caused by hormones, and is referred to medically as androgenetic alopecia.

Male pattern hair loss on the frontal hairline

Hair thinning on the male frontal hairline


Male pattern hair loss at the crown at the back of the head

Hair thinning at the crown at the back of the head.

Men have about 100,000 hairs at their peak in their early teens. By the time they first notice hair loss, they have already lost half their hair or about 50,000 hair follicles.

TrichoStem® Hair Regeneration’s Almost 100% Success Rate in Male

Hair loss does not happen overnight, rather hairs grow, then shed, then grow again. Hair loss occurs when hair grows back progressively thinner in each cycle, until it becomes so thin that it disappears and stops growing altogether. The treatment stops hair loss progression by reversing the hair thinning process – instead of hairs growing progressively thinner, hair grows back thicker, even darker.

Over the past five years, TrichoStem® Hair Regeneration has proven effective in 99.9% of male patients that receive the treatment. For the overwhelming majority of patients, this is a onetime treatment. This is important to note because of similar treatments need regular follow treatments, or don’t work until the second or subsequent treatment.

TrichoStem® Hair Regeneration is made up primarily of its activator platelet-rich plasma (PRP) that is taken from your own blood prior to the procedure, and ACell’s extracellular matrix as the main active ingredient. Both PRP and extracellular matrix are wound healing materials: the platelets of PRP are what heal cuts, ECM uses the regenerative qualities of porcine bladder for advanced reconstructive surgery. The combined wound healing materials trigger a wound healing response in the scalp that spurs the production of adult stem cells. The response of your own activated stem cells makes the hair follicles (specifically the root of the follicle called the dermal papilla) react by renewing the largely inactive hair growth cycle. Hairs that were growing thinner now have the renewed vigor to grow thicker, healthier hair, and as a side effect, darker hair. TrichoStem® Hair Regeneration does not contain drugs, and works on men who did not respond to finasteride (Propecia) therapy.

hair regeneration before and after

Man who didn’t respond to finasteride (Propecia) gains hair through TrichoStem® Hair Regeneration non-surgical treatment.

TrichoStem® Hair Regeneration is Low to No Maintenance

All other hair loss treatments need some regular maintenance.

Surgical hair transplantation does not stop hair loss, so hair does thin and fall out even after a transplant. If hair transplant patients do not receive additional treatment to stop their native hair from thinning, they will need additional hair transplants until their donor area runs out.

Finasteride (Propecia) is 5mg pill that is taken daily to stop the enzyme 5 alpha reductase from turning testosterone to dihydrotestosterone (DHT) to prevent hair thinning in DHT-sensitive hair follicles. If daily intake of the pill stops, hair will revert back within a year to the thinned state it was in prior to use. However, the possible sexual side effects of finasteride, can actually continue after use is discontinued. The well known side effects of finasteride discourage many patients from taking it. Finasteride is not approved to be taken by women, and does not work in all men.

Minoxidil (Rogaine) is a topic treatment that doesn’t stop hair from thinning, but does extend the active hair growth phase (anagen) and delays the hair shedding phase (telogen) so more hair is present on the head. Minxodil needs to be applied twice daily. If use is discontinued, the hair growth cycle reverts to its regular timing, and hair looks the same as it did prior to treatment. Many minoxidil users don’t see enough changes in their hair to bother continuing with twice daily application.

Platelet-rich plasma (PRP) injections for hair loss need regular treatment sessions every few months, and may need a higher frequency of injections when the therapy first starts. While PRP is used in TrichoStem® Hair Regeneration as an activator, using it alone for hair loss treatment produces minimal, varied, and inconsistent results. PRP injections don’t work on everyone.

TrichoStem® Hair Regeneration is a onetime treatment, with regular follow ups to monitor progress every few months. In select patients with advanced hair loss, a second treatment may be done after 1-2 years. Most TrichoStem® Hair Regeneration patients avoid a hair transplant completely because the density they receive from the non-surgical treatment exceeds the results of not one, but two hair transplants. The TrichoStem® Hair Regeneration treatment also costs about half of hair transplant surgery. In patients who have completely lost hair in certain parts of the scalp, a hair transplant can be performed with TrichoStem® Hair Regeneration to increase graft survival, thicken surrounding native hair, and stop continued hair loss.

Longevity of the TrichoStem® Hair Regeneration Treatment

After 5 years of administering the TrichoStem® Hair Regeneration treatment, its exact longevity is still not known. To manage expectations, Dr. Amiya Prasad tells his patients that treatment lasts at least 3-5 years. However, after 5 years of performing the treatment, no trend is seen of hair regressing into a state of thinning. No patient, not even the earliest ones, have returned for another treatment as their thickened hair growth has been maintained. As time goes on, the longevity of the TrichoStem® Hair Regeneration treatment continues to be monitored.

Hair Transplants and TrichoStem® Hair Regeneration

The overwhelming majority of TrichoStem® Hair Regeneration patients were considering hair transplants prior to treatment, but were able to avoid hair transplantation altogether after treatment. TrichoStem® Hair Regeneration is a true hair transplant alternative because it can provide better hair density than a hair transplant by thickening hair that has thinned, which is why the treatment can exceed the results of not one, but two hair transplant sessions. Nature spaces hair density much closer together than what can be achieved through hair transplantation because close density in a hair transplant will damage adjacent hair follicles, causing more hair loss.

TrichoStem® Hair Regeneration costs about half of a hair transplant, contains no drugs, does not involve surgery, can be performed in a fraction of the time, and unlike a hair transplant, it can prevent future hair loss.

While TrichoStem® Hair Regeneration can replace a hair transplant, it can also be used in conjunction, or shortly after hair transplant surgery. Combining the wound healing materials of platelet-rich plasma (PRP) and extracellular matrix by ACell helps to heal hair grafts, increase the survival rate of hair grafts, thickens the native hair surrounding transplanted hair, and most of all, stops hair loss progression so future hair transplants can be avoided.

hair transplant frontal area

A hair transplant is performed in completely bald areas, with TrichoStem® Hair Regeneration used in conjunction to prevent the need for more hair transplants in the future. The additional treatment thickened surrounding native hair, and also increased the survival rate of transplanted hair.

Cause of Male Pattern Loss

DHT – the Primary Culprit

The hormone dihydrotestosterone (DHT) is the primary cause of male pattern hair loss that makes up 95% of male hair loss cases. Dihydrotestosterone (DHT) is a byproduct of testosterone’s interaction with Type II 5-alpha reductase. Type II 5-alpha reductase is contained in the oil glands of hair follicles.DHT shrinks sensitive and susceptible hair follicles. As follicles shrink, hair becomes progressively thinner. Total pattern baldness occurs when thinning hair becomes so miniaturized that it stops growing altogether. Unfortunately, this hair-follicle sensitivity is genetic, shared by men within familial lines. While DHT is present in all men and women, not everyone has DHT-sensitive hair follicles.

DHT causing hair to thin

Hair follicles that are sensitive to DHT grow back thinner with each hair growth cycle. If left untreated, these hairs will eventually disappear altogether.

There are areas of the head that are genetically resistant to the effects of DHT, even in the baldest men. These areas are where donor hair is taken during hair transplants. It is important to note that follicular unit extraction (FUE) method of graft harvesting takes donor hair from outside this permanent zone, as this method cannot obtain as many grafts as follicular unit transplantation (FUT), also known as the Strip Method.

FUT vs FUE donor area

The donor area/permanent zone is an area of hair that is genetically resistant to DHT, so it is not prone to thinning. This limited area is where grafts are taken for hair transplants.

Attempts to Hide Hair Loss Makes it More Visible

To compensate for hair loss, some men opt for toupees and “comb-overs” in a more obvious, futile attempt to hide patchy, bald spots.

While some men who choose to shave off remaining hair actually look better bald, others simply can’t do away with a bare head.

visible hair plugs

Hair plugs are visible when transplanted hair remains, but native hair around it has thinned out and disappeared. Hair transplants do not stop progressive hair loss, so treatments like TrichoStem® Hair Regeneration are needed with hair transplants to prevent visible hair plugs, and more importantly, prevent the need for expensive, repeat hair transplants.

A common way to hide hair loss, which only draws more attention to it, are visible hair plugs. Hair plugs are not the result of bad hair transplants, rather the result of hair continuing to thin and disappear years after a transplant. Hair Transplants on their own do not stop continued hair loss like the TrichoStem® Hair Regeneration treatment. Hair plugs are actually transplanted hair that are genetically resistant to hair thinning since they are taken from the permanent zone at the back of the head. However, after the transplant, the transplanted hairs remain in place since they do not thin, while the native hair around them gradually thins with each growth cycle, and eventually becomes too thin to be seen, or disappears altogether.

Other Common Causes of Hair Loss in men:

Alopecia Areata

Alopecia areata is a common autoimmune skin disease which affects approximately 1.7% of the overall population, including more than 4.7 million people in the United States.

The disease can occur in both males and females, with no bias on race or age. Contributing factors that make an individual susceptible to alopecia areata include genetics, stress, hormones, allergies, viruses, and even toxins.

Since alopecia areata can result in hair loss on every part of the body, it can have a psychological impact on those affected. The condition can disrupta person’s personal and work life, even if it is not life-threatening or contagious.

In the case of alopecia areata, hair follicles are attacked by a person’s own immune system (white blood cells, in particular), somehow mistaking them to be threats to the body. This results in hair loss, which can occur abruptly, sometimes in a matter of days.

Alopecia areata often starts as circular, smooth bald patches on the scalp.Many who have one or two small patches can make a full recovery within two years even without treatment. At times,alopecia areata can progress to total hair loss on the scalp (alopecia totalis) or complete hair loss on the body (alopecia universalis).

To get the proper diagnosis of what is causing your hair loss, you can book an appointment at our Manhattan location at (212) 265-8877, or our Garden City, Long Island location at (516) 742-4636, or our new TrichoStem® Hair Regeneration center in Vienna, Virginia at (phone number to follow) or fill out the contact form below and we will contact you.

Schedule An Appointment Today!

To schedule a consultation with Dr. Amiya Prasad or a TrichoStem® doctor, submit the form below or call our Manhattan office at (646) 461-8547 or Garden City Long Island Office at (516) 535-9479. Our phones are open 24 Hours a Day / 7 Days a Week. Virtual consultations through Skype or through sending your hair loss details are also available. Patient Financing options available for qualified candidates.








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